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    Neuroscience Journal Publications

    This page includes links to Lilly sponsored clinical trials that have been published in peer reviewed journals over the last 3 years. Each section is sorted by product and may be expanded by each phase. The list of publications below is limited to products that have been approved for use and may contain information about doses, delivery devices, uses, formulations and populations different from product labeling. Clinical decisions should be based on the full safety and efficacy information contained in the product's Full Prescribing Information in the provided link below.

    If you have questions about a Lilly study not listed below or would like to request an electronic copy of one of the journal publications on this page, please Contact Lilly services.

    Amyvid

    Full Prescribing Information

    Radiation dosimetry and pharmacokinetics of florbetapir (18F) in Japanese subjects
    Published Date: May 28, 2019
    Standardization of amyloid quantitation with florbetapir standardized uptake value ratios to the Centiloid scale
    Published Date: July 11, 2018

    Efficacy and Limitations of rCBF-SPECT in the Diagnosis of Alzheimer's Disease With Amyloid-PET
    Published Date: April 9, 2019

    Efficacy and Limitations of rCBF-SPECT in the Diagnosis of Alzheimer's Disease With Amyloid-PET
    Published Date: April 9, 2019

    No Publications.

    Cymbalta

    Full Prescribing Information

    No Publications.

    No Publications.

    Relationship Between Pain Reduction and Improvement in Health-Related Quality of Life in Patients with Knee Pain Due to Osteoarthritis Receiving Duloxetine: Exploratory Post Hoc Analysis of a Japanese Phase 3 Randomized Study
    Published Date: January 20, 2020
    Maintenance of effect of duloxetine in Chinese patients with pain due to osteoarthritis: 13-week open-label extension data
    Published Date: April 23, 2019
    Analysis of HAM-D scores and working ability in an observational study of Japanese patients with major depressive disorder and painful physical symptoms treated with duloxetine or SSRI monotherapy
    Published Date: April 5, 2019
    Clinical meaningfulness of duloxetine's effect in Chinese patients with chronic pain due to osteoarthritis: post hoc analyses of a phase 3 randomized trial
    Published Date: March 21, 2019
    An Open-Label, 52-Week, Phase III Trial of Duloxetine in Japanese Patients with Chronic Low Back Pain
    Published Date: March 11, 2019
    Efficacy of duloxetine by prior NSAID use in the treatment of chronic osteoarthritis knee pain: A post hoc subgroup analysis of a randomized, placebo-controlled, phase 3 study in Japan
    Published Date: August 18, 2018

    Analysis of HAM-D scores and working ability in an observational study of Japanese patients with major depressive disorder and painful physical symptoms treated with duloxetine or SSRI monotherapy
    Published Date: April 5, 2019
    Clinical outcomes of patients with major depressive disorder treated with either duloxetine, escitalopram, fluoxetine, paroxetine, or sertraline
    Published Date: September 26, 2018
    Duloxetine in patients with diabetic peripheral neuropathic pain in Japan: a randomized, double-blind, noninferiority comparative study with pregabalin
    Published Date: September 13, 2018

    Emgality

    Full Prescribing Information

    Population Pharmacokinetics of Galcanezumab, an Anti-CGRP Antibody, Following Subcutaneous Dosing to Healthy Individuals and Patients With Migraine
    Published Date: September 4, 2019
    Comparison between prefilled syringe and autoinjector devices on patient-reported experiences and pharmacokinetics in galcanezumab studies
    Published Date: September 17, 2018

    Response to 'Do different treatment strategies of galcanezumab have similar effect on migraine?'
    Published Date: February 12, 2020
    Safety and tolerability of monthly galcanezumab injections in patients with migraine: integrated results from migraine clinical studies
    Published Date: January 17, 2020
    Population Pharmacokinetics of Galcanezumab, an Anti-CGRP Antibody, Following Subcutaneous Dosing to Healthy Individuals and Patients With Migraine
    Published Date: September 4, 2019
    Onset of efficacy and duration of response of galcanezumab for the prevention of episodic migraine: a post-hoc analysis
    Published Date: June 7, 2019
    A new era for migraine: Pharmacokinetic and pharmacodynamic insights into monoclonal antibodies with a focus on galcanezumab, an anti-CGRP antibody
    Published Date: March 27, 2019
    Applications of Bayesian statistical methodology to clinical trial design: A case study of a phase 2 trial with an interim futility assessment in patients with knee osteoarthritis
    Published Date: October 15, 2018
    Measures of Functioning in Patients With Episodic Migraine: Findings From a Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial With Galcanezumab
    Published Date: October 5, 2018
    CGRP blockade by galcanezumab was not associated with reductions in signs and symptoms of knee osteoarthritis in a randomized clinical trial
    Published Date: September 19, 2018
    Safety of galcanezumab in patients with episodic migraine: A randomized placebo-controlled dose-ranging Phase 2b study
    Published Date: May 28, 2018

    Assessment of immunogenicity from galcanezumab phase 3 trials in patients with episodic or chronic migraine
    Published Date: April 27, 2020
    Efficacy and Safety of Galcanezumab for the Preventive Treatment of Migraine: A Narrative Review
    Published Date: April 21, 2020
    Phase 3 randomized, placebo-controlled study of galcanezumab in patients with chronic cluster headache: Results from 3-month double-blind treatment
    Published Date: February 12, 2020
    Response to 'Do different treatment strategies of galcanezumab have similar effect on migraine?'
    Published Date: February 12, 2020
    Safety and tolerability of monthly galcanezumab injections in patients with migraine: integrated results from migraine clinical studies
    Published Date: January 17, 2020
    Correction to: Galcanezumab in episodic migraine: subgroup analyses of efficacy by high versus low frequency of migraine headaches in phase 3 studies (EVOLVE-1 & EVOLVE-2)
    Published Date: December 27, 2019
    Evaluation of Cardiovascular Outcomes in Adult Patients With Episodic or Chronic Migraine Treated With Galcanezumab: Data From Three Phase 3, Randomized, Double-Blind, Placebo-Controlled EVOLVE-1, EVOLVE-2, and REGAIN Studies
    Published Date: November 13, 2019
    Rapid Onset of Effect of Galcanezumab for the Prevention of Episodic Migraine: Analysis of the EVOLVE Studies
    Published Date: November 11, 2019
    Efficacy of galcanezumab in patients with episodic migraine and a history of preventive treatment failure: results from two global randomized clinical trials
    Published Date: November 6, 2019
    Efficacy of galcanezumab in patients with episodic migraine and a history of preventive treatment failure: results from two global randomized clinical trials
    Published Date: November 6, 2019
    Population Pharmacokinetics of Galcanezumab, an Anti-CGRP Antibody, Following Subcutaneous Dosing to Healthy Individuals and Patients With Migraine
    Published Date: September 4, 2019
    Erratum: Correction to 100% Response Rate to Galcanezumab in Patients With Episodic Migraine: A Post Hoc Analysis of the Results From Phase 3, Randomized, Double-Blind, Placebo-Controlled EVOLVE-1 and EVOLVE-2 Studies
    Published Date: July 11, 2019
    Trial of Galcanezumab in Prevention of Episodic Cluster Headache
    Published Date: July 11, 2019
    Two randomized migraine studies of galcanezumab: Effects on patient functioning and disability
    Published Date: July 3, 2019
    Galcanezumab in episodic migraine: subgroup analyses of efficacy by high versus low frequency of migraine headaches in phase 3 studies (EVOLVE-1 & EVOLVE-2)
    Published Date: June 28, 2019
    Efficacy of galcanezumab in patients with chronic migraine and a history of preventive treatment failure
    Published Date: June 3, 2019
    Effect of Galcanezumab Following Treatment Cessation in Patients With Migraine: Results From 2 Randomized Phase 3 Trials
    Published Date: April 3, 2019
    A new era for migraine: Pharmacokinetic and pharmacodynamic insights into monoclonal antibodies with a focus on galcanezumab, an anti-CGRP antibody
    Published Date: March 27, 2019
    Psychometric Validation of the Role Function Restrictive Domain of the Migraine Specific Quality-of-Life Questionnaire Version 2.1 Electronic Patient-Reported Outcome in Patients With Episodic and Chronic Migraine
    Published Date: March 12, 2019
    Letter to the editor regarding European Headache Federation guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention
    Published Date: March 1, 2019
    Preventive effects of galcanezumab in adult patients with episodic or chronic migraine are persistent: data from the phase 3, randomized, double-blind, placebo-controlled EVOLVE-1, EVOLVE-2, and REGAIN studies
    Published Date: December 29, 2018
    Analysis of Initial Nonresponders to Galcanezumab in Patients With Episodic or Chronic Migraine: Results From the EVOLVE-1, EVOLVE-2, and REGAIN Randomized, Double-Blind, Placebo-Controlled Studies
    Published Date: November 21, 2018
    Galcanezumab in chronic migraine: The randomized, double-blind, placebo-controlled REGAIN study
    Published Date: November 16, 2018
    Patient satisfaction, health care resource utilization, and acute headache medication use with galcanezumab: results from a 12-month open-label study in patients with migraine
    Published Date: November 13, 2018
    A phase 3, long-term, open-label safety study of Galcanezumab in patients with migraine
    Published Date: November 9, 2018
    100% Response Rate to Galcanezumab in Patients With Episodic Migraine: A Post Hoc Analysis of the Results From Phase 3, Randomized, Double-Blind, Placebo-Controlled EVOLVE-1 and EVOLVE-2 Studies
    Published Date: October 21, 2018
    Comparison between prefilled syringe and autoinjector devices on patient-reported experiences and pharmacokinetics in galcanezumab studies
    Published Date: September 17, 2018
    Efficacy and safety of galcanezumab for the prevention of episodic migraine: Results of the EVOLVE-2 Phase 3 randomized controlled clinical trial
    Published Date: May 31, 2018
    Evaluation of Galcanezumab for the Prevention of Episodic Migraine: The EVOLVE-1 Randomized Clinical Trial
    Published Date: May 29, 2018

    No Publications.

    Reyvow

    Full Prescribing Information

    Effects of Lasmiditan on Cardiovascular Parameters and Pharmacokinetics in Healthy Subjects Receiving Oral Doses of Propranolol
    Published Date: January 16, 2020
    Abuse Potential of Lasmiditan: A Phase 1 Randomized, Placebo- and Alprazolam-Controlled Crossover Study
    Published Date: November 20, 2019

    Issues Impacting Adverse Event Frequency and Severity: Differences Between Randomized Phase 2 and Phase 3 Clinical Trials for Lasmiditan
    Published Date: January 14, 2020

    Issues Impacting Adverse Event Frequency and Severity: Differences Between Randomized Phase 2 and Phase 3 Clinical Trials for Lasmiditan
    Published Date: January 14, 2020
    Trajectory of migraine-related disability following long-term treatment with lasmiditan: results of the GLADIATOR study
    Published Date: February 24, 2020
    Lasmiditan for the acute treatment of migraine: Subgroup analyses by prior response to triptans
    Published Date: November 19, 2019
    Onset of Efficacy Following Oral Treatment With Lasmiditan for the Acute Treatment of Migraine: Integrated Results From 2 Randomized Double-Blind Placebo-Controlled Phase 3 Clinical Studies
    Published Date: September 30, 2019
    Lasmiditan for acute treatment of migraine in patients with cardiovascular risk factors: post-hoc analysis of pooled results from 2 randomized, double-blind, placebo-controlled, phase 3 trials
    Published Date: August 29, 2019
    Interim results of a prospective, randomized, open-label, Phase 3 study of the long-term safety and efficacy of lasmiditan for acute treatment of migraine (the GLADIATOR study)
    Published Date: August 21, 2019
    Effect of a rescue or recurrence dose of lasmiditan on efficacy and safety in the acute treatment of migraine: findings from the phase 3 trials (SAMURAI and SPARTAN)
    Published Date: August 13, 2019
    Efficacy and safety of lasmiditan in patients using concomitant migraine preventive medications: findings from SAMURAI and SPARTAN, two randomized phase 3 trials
    Published Date: July 24, 2019
    Sustained responses to lasmiditan: Results from post-hoc analyses of two Phase 3 randomized clinical trials for acute treatment of migraine
    Published Date: July 3, 2019
    Safety findings from Phase 3 lasmiditan studies for acute treatment of migraine: Results from SAMURAI and SPARTAN
    Published Date: July 3, 2019
    Characterization of Dizziness After Lasmiditan Usage: Findings From the SAMURAI and SPARTAN Acute Migraine Treatment Randomized Trials
    Published Date: June 1, 2019
    Phase 3 randomized, placebo-controlled, double-blind study of lasmiditan for acute treatment of migraine
    Published Date: May 28, 2019
    Lasmiditan is an effective acute treatment for migraine: A phase 3 randomized study
    Published Date: December 11, 2018

    No Publications.

    Strattera

    Full Prescribing Information

    No Publications.

    No Publications.

    No Publications.

    No Publications.

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